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Brands : Procardia (Nifedipine)

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Available doses&packages : Commercial Name: Procardia
Active Ingredient: Nifedipine
Utilization: Treats blood vessels
Available Dosage: 20mg

Hypertension or high blood pressure occurs when blood vessels constantly experience high blood pressure. Through the blood vessels, blood is transferred from the heart to all other parts and organs of your body. With each contraction, the heart pumps blood into the vessels. So, the higher this pressure, the harder is for your heart to pump blood.
Hypertension can lead to numerous problems up to heart attack or heart failure. So timely blood pressure treatment is important in order not to allow the aneurysms to develop and appear vulnerable places in which the vessels may be blocked and torn.
High blood pressure treatment at home is not a good idea because the disorders may be very serious. The high blood pressure can lead to bleeding in the brain and the development of stroke.
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Procardia is a calcium blocker.

Release form and composition of Procardia

The dosage form is a pack of yellow color (10 pieces in blisters, in a cardboard box there are 5 blisters). Active ingredients are nifedipine, in 1 tablet - 10 mg.

Excipients: wheat starch, gelatin, magnesium stearate, lactose, microcrystalline cellulose PH101, talc.

Procardia is a selective blocker of slow calcium channels. The drug has antianginal, antihypertensive and vasodilating action. It reduces the current of calcium ions inside the smooth muscle cells of the peripheral and coronary arteries, as well as inside the cardiomyocytes.

In large doses, Procardia inhibits the release of calcium ions from the depot inside the cells. It reduces the number of functioning calcium channels, without affecting the time of their recovery, inactivation, and activation.

Procardia dissociates the processes of contraction and arousal in the smooth muscles of blood vessels mediated by calmodulin and in the heart muscle mediated by troponin and tropomyosin. In therapeutic doses, the drug normalizes the transport of calcium ions through the membrane, broken in certain pathological conditions, such as arterial hypertension.

Procardia does not affect the tone of the veins. It reduces spasm, dilates the peripheral and coronary vessels (mainly arterial), lowers blood pressure and total peripheral vascular resistance, reduces myocardial tone, afterload, and oxygen demand of the heart muscle, and prolongs the left ventricular diastolic relaxation.

Under its influence, the coronary blood flow is increased, the blood supply to the ischemic zones of the myocardium is improved, and the functioning of the collaterals is activated.

Procardia Almost does not affect atrioventricular and sinoatrial nodes and does not have an antiarrhythmic effect. Procardia Enhances blood flow in the kidneys causes a moderate excretion of sodium in the urine. The clinical effect occurs after 20 minutes and lasts from 4 to 6 hours.