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Zofran is a prescription medicine that has been licensed to prevent nausea and vomiting due to several causes.
The dose of Zofran depends on the type of chemotherapy -high risk for nausea and vomiting or medium risk.
High-risk chemotherapy: The dose of Zofran for high-risk chemotherapy is Zofran 24 mg (taken as three 8 mg tablets) 30 minutes before chemotherapy.
Medium-risk chemotherapy: The dose of Zofran for medium-risk chemotherapy is Zofran 8 mg twice daily. The first dose should be taken 30 minutes before chemotherapy, and the second dose should be taken eight hours after the first dose. After that, Zofran should be taken twice a day (about every 12 hours) until one to two days after chemotherapy. 
If you develop any sexual side effects while taking Zofran, be sure to talk with your healthcare provider
If you miss a dose of Zofran and are taking it regularly, you should take it as soon as you can remember it. If you miss for long time and it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at a time to compensate fro the missed dose.
Zofran should be stored at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store it away from heat, moisture, and direct light, in a tight, light-resistant container. Do not store in the bathroom. Keep Zofran out of the reach of children.