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In general, depression is treated with a combination therapy of medication and psychotherapy. Regarding pharmacological treatment, there are currently many alternatives to address the disease.
Classical antidepressants are constituted by a central ring with seven elements and a terminal nitrogen that contains three elements (tertiary amines) and two elements (secondary amines). Tertiary amines include a wide range of types, while secondary amines include only three of them: desipramine, protriptyline, and nortriptyline.
What these drugs do is prevent the reuptake of serotonin, as well as norepinephrine, which, as a consequence, leads to an increase in the levels of both neurotransmitters in the brain.
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Sertraline is used to treat depression, panic attacks, obsessive-compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).

This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a particular natural substance (serotonin) in the brain.